Mufulira Mine discovered in June 1923 when two experienced prospectors, Moir and Grey, who were working for the Rhodesian Congo Border Concession, found copper carbon stains.
It was only in 1928, that serious work commenced on Mufulira Mine. This was partly because of transport problems and administrative changes, but local beliefs also delayed work.
Because of World Depression, all operations on the mine in Mufulira were suspended in 1931. The mine started producing again in 1933 with the introduction of backfill and cave mining in 1944.
On the 25th September 1970 an underground breach of a tailings dam occurred at the Mufulira Mine. As the night shift crew were on duty the tailings dam above them collapsed causing nearly 1 million tonnes of tailings to fill the mine workings killing 89 miners.
On 1st April 2000, Mopani Copper Mines PLC purchased the ZCCM assets at Mufulira and Nkana, consisting of the underground mine, concentrator, smelter, refinery and cobalt plant, from the government.
The company installed ISA smelt furnace, Matte Settling Electric Furnace, oxygen plant, at the Mufulira smelter during 2004 and 2005